Photo: Richard Reynolds holding a brain in the tissue bank

Stop MS history

Today is the most exciting time there's ever been for the treatment and management of MS. We know what everyone with MS wants - no relapses, no build up of disability and no uncertainty - and we know how to do it. We need to raise £100 million for ground breaking research that will make it happen.

Twenty-five years ago there were no disease modifying therapies (DMTs) for MS. Today there are over a dozen licensed treatments for people with relapsing forms of MS, and one for some people with primary progressive MS.

But these treatments only work for some and there are no treatments that can completely stop the progression of MS.

Decades of research have led to major advances in our understanding of MS. We’re now in a position to build on that success and Stop MS once and for all.


Donate now to Stop MS

Our research story

We were founded in 1953 by Richard and Mary Cave, who had MS. We've been raising money for research ever since, funding our first symptom management project in 1959.

Since then, we’ve invested £220 million in research, which has led to significant progress in MS treatments. And we've been led every step of the way by our community of people who know MS.

Some of our biggest milestones include:

Explore our research history

We've come a long way since 1953. But we need to do more. And that means a significant investment.

Together we can stop MS

Today multiple sclerosis is relentless, painful and exhausting.

But tomorrow we believe can change that.

You can hear an audio described version of this video on our YouTube channel.

Support our Stop MS Appeal

Stop MS Appeal history

We started laying the groundwork for the Stop MS Appeal in 2012 when we recruited our Stop MS steering group. They developed our vision to make MS history.

Since then we've worked closely with our steering group, Appeal Board members and Pioneers to raise money through fantastic events like our St Paul's Carol Concert and Jacqueline du Pré Tribute Concerts.

Behind the scenes, we've invested time and money building our Expert Consortium of researchers and designing incredible new trials.

For four and a half years Stop MS was a discreet research fundraising appeal. During that time, thanks to our amazing MS Pioneers, we raised an incredible £47 million.

Our Stop MS Appeal went live to the public on 8 October 2019.

An end to MS is in our grasp. Raising £100 million over ten years will revolutionise treatments and change the course of MS for everyone.

Donate now to Stop MS

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“With a dramatic increase in investment over the next 10 years, there is a genuine prospect we can transform treatment for everyone with MS, including people with progressive forms. The Stop MS Appeal is pivotal to us achieving this.” Professor Alan Thompson (Consultant neurologist and Chair of Scientific Steering Committee of the International Progressive MS Alliance)