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How can we measure myelin repair in the brain?

Image of a mouse brain showing myelin (gold) running through the brain
Lead researcher:
Professor Robin Franklin
Based at:
University of Cambridge
MS Society funding:
£282,280
Status:
Active

About the project

In MS, our immune system attacks the protective myelin coating surrounding nerve cells. Specialist cells in the brain are able to repair damaged myelin. Researchers are developing treatments to improve myelin repair, but without being able to measure myelin growth, it is hard to test how good they are.

This project will target living myelin producing cells in the brain so they can be viewed by MRI. This is achieved by engineering cells that light up depending on how much myelin repair is taking place.

How will it help people with MS?

If we can measure myelin growth then we can see which new treatments are working best for people with MS. This will speed up drug development and deliver new treatments for MS more quickly.

The difference you can make

For so many people living with MS, fatigue has a significant impact on their daily lives. Help us find more effective treatments by supporting research like this.